Gene expression–based tests are proposed as diagnostic aids in cases with uncertain diagnoses. This study directly compared the diagnostic accuracy of IHC analysis versus molecular classification using a 92-gene RT-PCR assay for determination of the primary tumor site. air jordan canada This prospectively defined blinded study of diagnostically challenging cases included 131 high-grade, primarily metastatic tumors.
Nike Mid Blazer Women Cases were reviewed and reference diagnoses established through clinical correlation. air jordans canada Blinded FFPE sections were evaluated by either IHC/morphology analysis or the 92-gene assay. The final analysis included 122 cases. The 92-gene assay demonstrated overall accuracy of 79% (95% CI, 71% to…9 ( n = 39) IHC stains Cheap Nike Trainers Wholesale were used, respectively, Nike Shox Outlet versus 81%, 85%, and 69%, respectively, with the 92-gene assay.
Results from this blinded series of high-grade metastatic cases Womens Nike Trainers Black demonstrate superior accuracy with the 92-gene assay versus standard-of-care IHC analysis and strongly support the nike air jordan canada diagnostic utility of molecular classification in difficult-to-diagnose metastatic cancer.